![]() ![]() Two measures of iron depletion were assessed: 1) Iron Deficient Erythropoiesis (IDE), an intermediate stage of iron depletion was defined as the upper 2.5% of the distribution of log(soluble transferrin receptor/ferritin) in the FT/RA male cohort at enrollment, corresponding roughly to ferritin < 26 ng/mL and 2) Absent Iron Stores (AIS), defined as ferritin < 12 ng/mL.Ī detailed summary was prepared of donor presentations for allogeneic WB or RBC apheresis donation and productivity over the full 4-year REDS-II data collection. Donors with no prior donation history (FT), or not within the last two years (RA) entered the “First-Time/Reactivated” donor cohort (FT/RA), while females with 2 or males with 3 WB donations in the prior 12 months entered the Frequent Repeat (RPT) cohorts. 3, 4 Briefly, 2425 donors were recruited into 4 cohorts stratified by gender and recent donation history and followed for 15–24 months. RISE Study Dataset: The RISE study of iron deficiency in blood donors, has been described elsewhere. ![]()
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